Dep
Dr. Lisa Mehlmann
Department of Cell Biology

Lisa Mehlmann
Assistant Professor

Department of Cell Biology
University of Connecticut Health Center
263 Farmington Ave
Farmington, CT 06032

860 679 2703
860 679 1269 (fax)
lmehlman@neuron.uchc.edu


Research interests:

Signaling events that regulate meiosis

Recent publications

Mehlmann, L.M., Kalinowski, R.R., Ross, L.F., Parlow, A.F., Hewlett, E.L. and Jaffe, L.A. 2006. Meiotic resumption in response to luteinizing hormone is independent of a Gi family G protein or calcium in the mouse oocyte. Dev. Biol. 299:345-355. pdf file

Mehlmann, L.M. 2005. Stops and Starts in Mammalian Oocytes: Recent Advances in Understanding the Regulation of Meiotic Arrest and Oocyte Maturation. Reproduction 130:791-798.pdf file

Freudzon, L., Norris, R.P., Hand, A.R., Tanaka, S., Saeki, Y., Jones, T.L.Z., Rasenick, M.M., Berlot, C.H., Mehlmann, L.M., and Jaffe, L.A. 2005.  Regulation of meiotic prophase arrest in mouse oocytes by GPR3, a constitutive activator of the Gs G protein.  J. Cell Biol. 171:255-265.  pdf file

Mehlmann, L.M.  2005. Oocyte-specific expression of GPR3 is required for the maintenance of meiotic arrest in mouse oocytes. Dev. Biol. 288:397-404.pdf file

Mehlmann, L.M., and Jaffe, L.A. 2005. SH2 domain-mediated activation of a SRC family kinase is not required to initiate Ca2+ release at fertilization in mouse eggs.  Reproduction: 129: 557-564.pdf file

Mehlmann, L.M., Saeki, Y., Tanaka, S., Brennan, T.J., Evsikov, A.V. Pendola, F.L., Knowles, B.B., Eppig, J.J., and Jaffe, L.A.   2004.   The G s -linked receptor GPR3 maintains meiotic arrest in mammalian oocytes.   Science: 306: 1947 - 1950.  pdf file

Kalinowski, R.R., Berlot, C.H., Jones, T.L.Z., Ross, L.F., Jaffe, L.A., and Mehlmann, L.M.   2004.   Maintenance of meiotic prophase arrest in vertebrate oocytes by a G s protein-mediated pathway.   Dev. Biol. 267: 1-13. pdf file

Mehlmann, L.M., Jones, T.L.Z., and Jaffe, L.A.   2002.   Meiotic arrest in the mouse follicle maintained by a G s protein in the oocyte.   Science 297:1343-1345. pdf file

Runft, L.L., Jaffe, L.A., and Mehlmann, L.M.   2002.   Egg activation at fertilization: Where it all begins.   Dev. Biol. 245:237-254. pdf file

 

 

Department of Cell Biology Faculty

UConn Health Center